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MYP_026979
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
12 amino acids
C65H94N16O18
Standard
Sequence
HPFAQTQSLVYP
Physicochemical Analysis
1387.54 Da
6.74
-0.15
-0.41
-0.0128
-0.30
0.22
0.18
57.15
65.00
0.1667
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
541.39
-4.47
17.0
19.0
38.0
99.0
5.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0093934 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 16.7%, T 33.3%, C 50.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
RECORD: Rec_0219160 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
26.0
IC50
PaperKohmura M., Nio N., Ariyoshi Y.. Inhibition of angiotensin-converting enzyme by synthetic peptide fragments of various beta-caseins. Agric. Biol. Chem., 54, 1101-1102, 1990.
RECORD: Rec_0263776 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
beta-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
26 μM
IC50
PaperInhibition of angiotensin-converting enzyme by synthetic peptide fragments of various β-caseins | Kohmura, M. et al. | DOI: 10.1271/bbb1961.54.1101 Evidence URLhttps://www.uniprot.org/uniprotkb/P02666/entry
RECORD: Rec_0267803 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperEvaluation of the allergenicity of goat milk, cow milk, and their lactosera in a guinea pig model PMID19233776 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19233776/
RECORD: Rec_0279464 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Casein-derived peptide
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-I converting enzyme
26 μM
IC50
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