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MYP_026960
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Basic Information
Dermaseptin-S1 (1-12)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
12 amino acids
C65H112N16O15S
Standard
Sequence
ALWKTMLKKLGT
Physicochemical Analysis
1389.75 Da
10.30
2.79
2.60
0.2327
0.06
0.50
0.09
7.67
105.83
0.0833
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
517.73
-1.85
19.0
19.0
48.0
97.0
2.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0328105 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
Vero cells
100 μM
CC50
PaperPubMed PMID: 20718719 PMID20718719 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20718719/
RECORD: Rec_0333298 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
293TT(embryonic human culture cells)
100 μM
CC50
PaperPubMed PMID: 20718719 PMID20718719 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20718719/
RECORD: Rec_0333678 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antiviral Hemolytic
PaperPubMed PMID: 20718719 PMID20718719 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20718719/
RECORD: Rec_0345597 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral Antiparasitic Antiprotozoal
Escherichia coli HB101
54 μM
MIC
PMID18676150;20718719 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18676150/
RECORD: Rec_0385502 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral Antiparasitic Antiprotozoal
Staphylococcus aureus Cowan 1
54 μM
MIC
PMID18676150;20718719 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18676150/
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