Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length187 amino acids

Chemical FormulaC919H1470N258O246S10

DescriptionStandard

        PTALPAAQEPMLLLAVTEVLANSAAFTYFTAGALRRNISGNMLPRRFPLQLRTKSMGLFAPELQERYPDQPMELHLSARRQPLLSCRPNALHGTLFSSAEAFVVLPNATRVPAFLLNIDANVTGKPTISRNRLGGTVSLKGPLCPPCAGLRGLPVPQVKRLENMLKFGLWLFGVPWANSECCPHPVP
    

Molecular Weight20389.73 Da

Isoelectric Point (pI)9.97

Net Charge (pH 7.0)9.19

Net Charge (pH 7.4) 8.88

Charge Density (pH 7.0) 0.0491

GRAVY Index0.05

Hydrophobic Moment 0.59

Boman Index0.09

Instability Index61.12

Aliphatic Index 93.96

Aromaticity 0.0695

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7899.16

LogP -92.66

H-bond Donors 272.0

H-bond Acceptors 268.0

Rotatable Bonds 641.0

Heavy Atoms 1433.0

Ring Count 40.0

Amide Bonds 202.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0323380 VERIFIED: NO

Provenance & Taxonomy

OrganismPluvianellus socialis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria