Peptide Database

Peptide NameR-486

Function Ontology

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Receptor modulation ▸ Antagonist

Neurological / Signaling ▸ Signaling peptide

Standard Statusnot Standard

Sequence Length7 amino acids

Chemical Formula-

Descriptioncontains X representing unresolved or non-standard residue

        DSFWXLM
    

Molecular Weight0.00 Da

Isoelectric Point (pI)0.00

Net Charge (pH 7.0)0.00

GRAVY Index0.00

Boman Index0.00

Instability Index0.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0420731 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitynoncanonical residue-containing peptide [Modified]

C-TermAmidation

Other ModsX placeholder represents β-alanine at position 5; C-terminal amidation

Bio-Activity Profile

Function

NK3 receptor antagonist Receptor antagonist Signaling peptide

TargetNK3 receptor (Rattus norvegicus central nervous system)

Methodintracerebroventricular NK3 antagonist cardiovascular/behavioral assay