MYP_026876
PTHrP-(7-34) (human, rat, mouse)
Neurological / Signaling
▸
Receptor modulation
▸
Agonist
Neurological / Signaling
▸
Receptor modulation
▸
Antagonist
Neurological / Signaling
▸
Signaling peptide
Standard
28 amino acids
C153H246N48O38
Standard
LLHDKGKSIQDLRRRFFLHHLIAEIHTA
3365.89 Da
9.98
2.11
1.70
0.0754
-0.30
0.68
-0.08
63.81
118.57
0.0714
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1396.93
-9.62
50.0
44.0
115.0
239.0
6.0
28.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0276334
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
GtoPdb peptide ligand
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Receptor antagonist
Signaling peptide
human PTH1 receptor
65 nM
receptor binding affinity assay
RECORD: Rec_0432978
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
GtoPdb peptide ligand
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Receptor antagonist
Signaling peptide
human PTH1 receptor
6.0±0.1 pKB
Schild analysis of cAMP antagonism
RECORD: Rec_0432979
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
GtoPdb peptide ligand
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Receptor antagonist
Signaling peptide
human PTH2 receptor
6.7 pIC50
receptor antagonism/binding assay