Peptide Database

Peptide NamePTHrP-(7-34) (human, rat, mouse)

Function Ontology

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Receptor modulation ▸ Antagonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC153H246N48O38

DescriptionStandard

        LLHDKGKSIQDLRRRFFLHHLIAEIHTA
    

Molecular Weight3365.89 Da

Isoelectric Point (pI)9.98

Net Charge (pH 7.0)2.11

Net Charge (pH 7.4) 1.70

Charge Density (pH 7.0) 0.0754

GRAVY Index-0.30

Hydrophobic Moment 0.68

Boman Index-0.08

Instability Index63.81

Aliphatic Index 118.57

Aromaticity 0.0714

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1396.93

LogP -9.62

H-bond Donors 50.0

H-bond Acceptors 44.0

Rotatable Bonds 115.0

Heavy Atoms 239.0

Ring Count 6.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0276334 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor antagonist Signaling peptide

TargetPTH1 receptor (Human); PTH2 receptor (Human)