Peptide Database

Peptide NameBrevinin-2SN4

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length72 amino acids

Chemical FormulaC339H555N89O106S10

DescriptionStandard

        MFTMKKPMLLLFFLGMISMSLCQDERGADEDDGGEMTEEEKRGAFGDLLKGVAKEAGLKLLNMAQCKLSGNC
    

Molecular Weight7894.22 Da

Isoelectric Point (pI)4.79

Net Charge (pH 7.0)-3.51

Net Charge (pH 7.4) -3.80

Charge Density (pH 7.0) -0.0488

GRAVY Index-0.14

Hydrophobic Moment 0.62

Boman Index0.04

Instability Index21.99

Aliphatic Index 75.97

Aromaticity 0.0556

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3147.68

LogP -28.77

H-bond Donors 109.0

H-bond Acceptors 113.0

Rotatable Bonds 281.0

Heavy Atoms 544.0

Ring Count 5.0

Amide Bonds 75.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0168684 VERIFIED: YES

Provenance & Taxonomy

OrganismSylvirana spinulosa [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetGram-negative and Gram-positive bacteria

RECORD: Rec_0271104 VERIFIED: NO