Peptide Database

Peptide NamePutative colicin activity protein (EC 3.1.-.-)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length170 amino acids

Chemical FormulaC792H1304N222O237S7

DescriptionStandard

        MGIALYSILPSEIAKDDPKMMSKIVTSLPAETVTNVQVSTLPLDQATVRVTKRVTDVVKDKRQHIAVVAGVPMSVPVVNAKPTRTPGVFRASFPGVPSLTLSTVKGLPASTTLPRGITEDKGRTASPAGFTFGGGSHEAVIRFPERKWAEAGLCISNRCSYLCTGKTTSG
    

Molecular Weight17952.63 Da

Isoelectric Point (pI)9.84

Net Charge (pH 7.0)8.66

Net Charge (pH 7.4) 8.26

Charge Density (pH 7.0) 0.0509

GRAVY Index-0.01

Hydrophobic Moment 0.84

Boman Index0.06

Instability Index44.53

Aliphatic Index 84.24

Aromaticity 0.0471

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7270.95

LogP -85.14

H-bond Donors 258.0

H-bond Acceptors 255.0

Rotatable Bonds 580.0

Heavy Atoms 1258.0

Ring Count 25.0

Amide Bonds 175.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0205818 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)