Peptide Database

Peptide NameDvAMP

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Venom / Toxin ▸ General toxin ▸ Toxicity

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC136H230N38O26S

DescriptionStandard

        EKKPWARLRFKFKLLKGLAKKMK
    

Molecular Weight2845.59 Da

Isoelectric Point (pI)11.33

Net Charge (pH 7.0)8.83

Net Charge (pH 7.4) 8.65

Charge Density (pH 7.0) 0.3839

GRAVY Index-0.88

Hydrophobic Moment 0.67

Boman Index-0.34

Instability Index-3.10

Aliphatic Index 76.52

Aromaticity 0.1304

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1079.78

LogP -3.19

H-bond Donors 39.0

H-bond Acceptors 36.0

Rotatable Bonds 104.0

Heavy Atoms 201.0

Ring Count 5.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0378571 VERIFIED: YES

Provenance & Taxonomy

OrganismDrosophila virilis [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Other ModsAPD analysis reveals that this sequence is similar (47.83%) to synthetic LL-14 K:35%; L: 17%. GRAVY: -0.883; mol Wt: 2845.6; mol formula: C136H231N38O26S1; mol ex coeff: 5550 Chemical modification: C-terminal amidation

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetPseudomonas aeruginosa CMCC 10104

Activity16 μg/mL

MethodMIC

RECORD: Rec_0405810 VERIFIED: YES