Peptide Database

Peptide NameDefensin beta 1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length68 amino acids

Chemical FormulaC328H517N91O95S9

DescriptionStandard

        MRTSYLLLFTLCLLLSEMASGDNFLTGLGHRSDHYNCVRSGGQCLYSACPIYTKIQGTCYHGKAKCCK
    

Molecular Weight7543.75 Da

Isoelectric Point (pI)8.75

Net Charge (pH 7.0)3.69

Net Charge (pH 7.4) 3.20

Charge Density (pH 7.0) 0.0542

GRAVY Index0.02

Hydrophobic Moment 0.56

Boman Index0.07

Instability Index38.75

Aliphatic Index 77.50

Aromaticity 0.1029

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7825.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2987.99

LogP -31.53

H-bond Donors 114.0

H-bond Acceptors 111.0

Rotatable Bonds 248.0

Heavy Atoms 523.0

Ring Count 11.0

Amide Bonds 71.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0022384 VERIFIED: NO

Provenance & Taxonomy

OrganismRhinopithecus roxellana [Animal]

FamilyDefensin

Tax ID61622

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0045913 VERIFIED: YES

Provenance & Taxonomy

OrganismChlorocebus aethiops [Animal]

FamilyBeta-defensin; Defensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic

RECORD: Rec_0214069 VERIFIED: NO

Provenance & Taxonomy

OrganismChlorocebus sabaeus [Animal]

FamilyDefensin

Tax ID60711

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic

RECORD: Rec_0295910 VERIFIED: NO

Provenance & Taxonomy

OrganismRhinopithecus bieti [Animal]

FamilyDefensin

Tax ID61621

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0331772 VERIFIED: YES

Provenance & Taxonomy

OrganismAllochrocebus preussi [Animal]

FamilyBeta-defensin; Defensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic