Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC153H258N44O46S4

DescriptionStandard

        NGVKPEPRITSVSLCTMGCQGSKLQTVICNWVK
    

Molecular Weight3578.21 Da

Isoelectric Point (pI)9.11

Net Charge (pH 7.0)2.73

Net Charge (pH 7.4) 2.48

Charge Density (pH 7.0) 0.0827

GRAVY Index-0.02

Hydrophobic Moment 0.56

Boman Index0.04

Instability Index19.12

Aliphatic Index 82.42

Aromaticity 0.0303

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1463.73

LogP -17.19

H-bond Donors 53.0

H-bond Acceptors 53.0

Rotatable Bonds 118.0

Heavy Atoms 247.0

Ring Count 4.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0250049 VERIFIED: NO

Provenance & Taxonomy

OrganismEnterococcus moraviensis ATCC BAA-383 [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence