Peptide Database

Peptide NameSLAY-screened peptide P3941

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC95H147N27O30S

DescriptionStandard

        ADPENSSLRCAPIFPGFTRT
    

Molecular Weight2179.41 Da

Isoelectric Point (pI)6.11

Net Charge (pH 7.0)-0.21

Net Charge (pH 7.4) -0.42

Charge Density (pH 7.0) -0.0105

GRAVY Index-0.39

Hydrophobic Moment 0.52

Boman Index-0.04

Instability Index52.47

Aliphatic Index 49.00

Aromaticity 0.1000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 912.26

LogP -11.21

H-bond Donors 32.0

H-bond Acceptors 31.0

Rotatable Bonds 64.0

Heavy Atoms 153.0

Ring Count 5.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0373100 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/