Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC371H604N102O93S10

DescriptionStandard

        MRVLLLILGVLTLLFIVPMARSFLGSQNCASENRHCRMKCETTEYAVRYCEDWTICCWAKKKKVKKKKMW
    

Molecular Weight8302.04 Da

Isoelectric Point (pI)9.61

Net Charge (pH 7.0)8.53

Net Charge (pH 7.4) 8.15

Charge Density (pH 7.0) 0.1218

GRAVY Index-0.02

Hydrophobic Moment 0.52

Boman Index-0.03

Instability Index37.81

Aliphatic Index 87.71

Aromaticity 0.1000

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3180.00

LogP -21.48

H-bond Donors 121.0

H-bond Acceptors 113.0

Rotatable Bonds 283.0

Heavy Atoms 576.0

Ring Count 12.0

Amide Bonds 72.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0405022 VERIFIED: NO

Provenance & Taxonomy

OrganismMesocricetus auratus [Animal]

FamilyBeta-defensin; Defensin

Tax ID10036

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic