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MYP_026696
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Basic Information
CPF-3
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
17 amino acids
C108H177N27O18
Standard
Sequence
KFWKLLKKALRLWAKVL
Physicochemical Analysis
2141.73 Da
11.39
5.76
5.54
0.3385
0.22
0.91
0.02
10.85
143.53
0.1765
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
752.50
1.68
28.0
24.0
74.0
153.0
5.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0396207 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
human red blood cells
PaperNovel antimicrobial peptide CPF-C1 analogs with superior stabilities and activities against multidrug-resistant bacteria. Chem Biol Drug Des. 2017 Nov;90(5):690-702. doi: 10.1111/cbdd.12988. PMID: 28371431. PMID28371431 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28371431/
RECORD: Rec_0396468 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa 2760
8 μg/mL
MIC
PaperNovel antimicrobial peptide CPF-C1 analogs with superior stabilities and activities against multidrug-resistant bacteria. Chem Biol Drug Des. 2017 Nov;90(5):690-702. doi: 10.1111/cbdd.12988. PMID: 28371431. PMID28371431 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28371431/
RECORD: Rec_0399053 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcuss aureus 725
8 μg/mL
MIC
PaperNovel antimicrobial peptide CPF-C1 analogs with superior stabilities and activities against multidrug-resistant bacteria. Chem Biol Drug Des. 2017 Nov;90(5):690-702. doi: 10.1111/cbdd.12988. PMID: 28371431. PMID28371431 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28371431/
RECORD: Rec_0399989 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli 780
16 μg/mL
MIC
PMID28371431 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28371431/
RECORD: Rec_0401256 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 27853
16 μg/mL
MIC
PaperNovel antimicrobial peptide CPF-C1 analogs with superior stabilities and activities against multidrug-resistant bacteria. Chem Biol Drug Des. 2017 Nov;90(5):690-702. doi: 10.1111/cbdd.12988. PMID: 28371431. PMID28371431 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28371431/
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