Peptide Database

Peptide NameHAL-1/15

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC65H107N19O14S

DescriptionStandard

        GMWSKLLGHLLR
    

Molecular Weight1410.73 Da

Isoelectric Point (pI)11.00

Net Charge (pH 7.0)1.85

Net Charge (pH 7.4) 1.59

Charge Density (pH 7.0) 0.1539

GRAVY Index0.25

Hydrophobic Moment 0.64

Boman Index0.17

Instability Index18.14

Aliphatic Index 130.00

Aromaticity 0.0833

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 536.04

LogP -1.99

H-bond Donors 20.0

H-bond Acceptors 18.0

Rotatable Bonds 47.0

Heavy Atoms 99.0

Ring Count 3.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0415541 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetHeLa

Activity14±2 μM

MethodIC50

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