Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC486H791N129O132S6

DescriptionStandard

        MKLFLVLIILLFEVLTDGARLKKCFNNITGYCRKKCKVGERYEIGCLSGKLRCVNDEEEKKHVSFKKPHQHSGEKLSVQQDYIILPTITIFTV
    

Molecular Weight10745.65 Da

Isoelectric Point (pI)9.18

Net Charge (pH 7.0)5.72

Net Charge (pH 7.4) 5.24

Charge Density (pH 7.0) 0.0615

GRAVY Index-0.10

Hydrophobic Moment 0.62

Boman Index-0.00

Instability Index22.59

Aliphatic Index 102.58

Aromaticity 0.0860

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4720.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4243.12

LogP -31.98

H-bond Donors 152.0

H-bond Acceptors 147.0

Rotatable Bonds 373.0

Heavy Atoms 753.0

Ring Count 13.0

Amide Bonds 98.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0065247 VERIFIED: NO

Provenance & Taxonomy

OrganismNomascus leucogenys [Animal]

FamilyDefensin

Tax ID61853

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence