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MYP_026626
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Basic Information
N-formyl-Met-Leu-Phe (fMLF)
Chemotaxis Regulator
Standard
3 amino acids
C20H31N3O4S
Standard
Sequence
MLF
Physicochemical Analysis
409.54 Da
5.28
-0.50
-0.72
-0.1665
2.83
0.31
0.96
6.67
130.00
0.3333
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
121.52
1.41
4.0
5.0
12.0
28.0
1.0
2.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0284317 VERIFIED: YES
Provenance & Taxonomy
Escherichia coli [Bacterium]
562
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Formylation
N-formylmethionine (fMLF)
Bio-Activity Profile
Chemotaxis Regulator Chemoattractant GPCR agonist
human formyl peptide receptor 2 (FPR2/ALX)
6.7±3.0 μM
EC50 (Ca2+ mobilization assay)
PaperStructural determinants for the interaction of formyl peptide receptor 2 with peptide ligands PMID24285541
RECORD: Rec_0432956 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Formyl peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
N-formylation
N-formylmethionine (fMLF)
Bio-Activity Profile
Chemotaxis Regulator Chemoattractant GPCR agonist
human formyl peptide receptor 1 (FPR1)
3.5±0.6 nM
EC50 (Ca2+ mobilization assay)
PaperStructural determinants for the interaction of formyl peptide receptor 2 with peptide ligands PMID24285541
RECORD: Rec_0432957 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Formyl peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
N-formylation
N-formylmethionine (fMLF)
Bio-Activity Profile
Chemotaxis Regulator Chemoattractant GPCR agonist
human formyl peptide receptor 1 (FPR1)
3.4±1.6 nM
IC50 (cAMP accumulation assay)
PaperStructural determinants for the interaction of formyl peptide receptor 2 with peptide ligands PMID24285541
RECORD: Rec_0432958 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Formyl peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
N-formylation
N-formylmethionine (fMLF)
Bio-Activity Profile
Chemotaxis Regulator Chemoattractant GPCR agonist
human formyl peptide receptor 2 (FPR2/ALX)
2.5±1.2 μM
IC50 (cAMP accumulation assay)
PaperStructural determinants for the interaction of formyl peptide receptor 2 with peptide ligands PMID24285541