Peptide Database

Peptide NameGaegurin-4

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Antiparasitic ▸ Antiprotozoal

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC165H287N45O49S2

DescriptionStandard

        GILDTLKQFAKGVGKDLVKGAAQGVLSTVSCKLAKTC
    

Molecular Weight3749.45 Da

Isoelectric Point (pI)9.51

Net Charge (pH 7.0)3.74

Net Charge (pH 7.4) 3.49

Charge Density (pH 7.0) 0.1010

GRAVY Index0.33

Hydrophobic Moment 0.67

Boman Index0.13

Instability Index4.90

Aliphatic Index 105.41

Aromaticity 0.0270

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1528.97

LogP -16.53

H-bond Donors 55.0

H-bond Acceptors 55.0

Rotatable Bonds 132.0

Heavy Atoms 261.0

Ring Count 1.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0417049 VERIFIED: YES

Provenance & Taxonomy

OrganismGlandirana rugosa [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermCyclization

Disulfide31-37

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Antiprotozoal

TargetStaphylococcus epidermidis

Activity10 μg/mL

MethodMIC

RECORD: Rec_0419189 VERIFIED: YES