Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length168 amino acids

Chemical FormulaC877H1304N198O256S8

DescriptionStandard

        NFQGIVYPAGNYTDPPYVTAPFNIPDQRDSMLYLAFSEYFFQTSSFAYYTAGAFNITIAEEFYFLFYSFQTCSHFNISTEIFGSIIPEVAKYSVTPHPVMLKLMATEVPIISLEKDLFTVEIQGSMEVFAVLPDSTTQSLFTMNTTANISISLNIFDQKLMGSLCLNR
    

Molecular Weight18973.43 Da

Isoelectric Point (pI)4.36

Net Charge (pH 7.0)-9.07

Net Charge (pH 7.4) -9.44

Charge Density (pH 7.0) -0.0540

GRAVY Index0.24

Hydrophobic Moment 0.55

Boman Index0.24

Instability Index43.88

Aliphatic Index 84.76

Aromaticity 0.1607

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 15025.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7198.73

LogP -64.93

H-bond Donors 245.0

H-bond Acceptors 257.0

Rotatable Bonds 599.0

Heavy Atoms 1339.0

Ring Count 39.0

Amide Bonds 183.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0049724 VERIFIED: NO

Provenance & Taxonomy

OrganismUrocolius indicus (Red-faced mousebird) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria