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MYP_026538
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Basic Information
Fabatin-1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Antimicrobial ▸ Antifungal ▸ Fungicidal activity
Plant bioactivity ▸ Plant defense peptide
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
47 amino acids
C213H353N75O61S9
Standard
Sequence
LLGRCKVKSNRFHGPCLTDTHCSTVCRGEGYKGGDCHGLRRRCMCLC
Physicochemical Analysis
5229.13 Da
9.12
5.94
5.46
0.1265
-0.42
0.43
-0.20
44.30
53.83
0.0426
1490.00
1990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2205.00
-27.77
89.0
79.0
175.0
358.0
6.0
47.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0010454 VERIFIED: YES
Provenance & Taxonomy
Broad bean [Plant]
Defensin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
It contains four disulfide bonds:5,47; 16,36; 22,43; 26,45
Bio-Activity Profile
Antimicrobial
Escherichia coli, Pseudomonas aeruginosa
PaperFabatins: new antimicrobial plant peptides.
RECORD: Rec_0030466 VERIFIED: YES
Provenance & Taxonomy
Vicia faba [Plant]
Defensin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
PaperPubMed PMID: 9103978 PMID9103978 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9103978/
RECORD: Rec_0042648 VERIFIED: YES
Provenance & Taxonomy
Vicia faba [Plant]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
E.hirae
PMID9103978 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9103978/
RECORD: Rec_0046710 VERIFIED: YES
Provenance & Taxonomy
Vicia faba [Plant]
Defensin
3906
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
1-47
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Pseudomonas aeruginosa
PaperPubMed PMID 9725750 | PubMed PMID 4910397 PMID9725750;4910397 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9725750/
RECORD: Rec_0078449 VERIFIED: YES
Provenance & Taxonomy
Vicia faba [Plant]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
PMID9103978 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9103978/
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