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MYP_026517
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Basic Information
SynB3
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
10 amino acids
C60H101N25O14
Standard
Sequence
RRLSYSRRRF
Physicochemical Analysis
1396.60 Da
12.00
4.76
4.55
0.4759
-1.88
0.60
-1.05
200.10
39.00
0.2000
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
695.41
-7.70
29.0
19.0
47.0
99.0
2.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0017173 VERIFIED: YES
Provenance & Taxonomy
Protein derived [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
NBD and TAMRA
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID12783857 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12783857/
RECORD: Rec_0032614 VERIFIED: YES
Provenance & Taxonomy
Protein derived [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
NBD and TAMRA
None
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID12783857 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12783857/
RECORD: Rec_0041664 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
SynB
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Conjugation with NBD and TAMRA
None
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery Antimicrobial
PMID12783857 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12783857/
RECORD: Rec_0109042 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Labelled with NBD and TAMRA
None
Bio-Activity Profile
Drug Delivery Vehicle Cell-penetrating peptide
PaperCPPsite: a curated database of cell penetrating peptides PMID22403286 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22403286/
RECORD: Rec_0111875 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
SynB/Protegrin
9823
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Fluorophore labeling
None
N-term detail: Labelled with NBD; lowercase source residues at positions 1,2,3,4,5,6,7,8,9,10 denote stereochemical modification
Bio-Activity Profile
Cell-penetrating peptide Antimicrobial
K562 cells
Fluorescence-based uptake assay
PMID12783857 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12783857/
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