Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length172 amino acids

Chemical FormulaC865H1331N199O255S8

DescriptionStandard

        QGIVYPAGNYTGSTCVAAPFTIPDQSDSMLHLAFSEHFFQSSSFAYYTAGAFNITIAEEVKSGKLLLFFFLLLQTCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPVISLEQDSLTVEIQGSMEVFAVLPDSTTQLLFTMNIAANTSIALNIFDQKLVGSLCLNR
    

Molecular Weight18854.52 Da

Isoelectric Point (pI)4.45

Net Charge (pH 7.0)-8.08

Net Charge (pH 7.4) -8.46

Charge Density (pH 7.0) -0.0470

GRAVY Index0.47

Hydrophobic Moment 0.55

Boman Index0.29

Instability Index44.75

Aliphatic Index 101.51

Aromaticity 0.1221

Extinction Coeff. Reduced 10430.00

Extinction Coeff. Oxidized 10555.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7175.98

LogP -70.30

H-bond Donors 246.0

H-bond Acceptors 257.0

Rotatable Bonds 607.0

Heavy Atoms 1327.0

Ring Count 31.0

Amide Bonds 186.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0393856 VERIFIED: NO

Provenance & Taxonomy

OrganismNycticryphes semicollaris [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria