Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length184 amino acids

Chemical FormulaC922H1402N210O287S7

DescriptionStandard

        QIDDLAEVDYSLSGLPAVFQPFIDLDLKGVVFPAGNHTDSPYMAASFTIPDQSDSMLSLAFSEYFFQSSSFAYYTAGAFNMTIAEETCSYFNINTEIFSSIIPEVAKYSVTPYPVMLKLMSTEIPFISLQQDSFTVEIQGSVEVLAILPDSTTQSLFTLNIAANTSISLNIFDQKLLGSLCLNR
    

Molecular Weight20244.68 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-15.15

Net Charge (pH 7.4) -15.47

Charge Density (pH 7.0) -0.0823

GRAVY Index0.29

Hydrophobic Moment 0.55

Boman Index0.24

Instability Index57.67

Aliphatic Index 95.43

Aromaticity 0.1250

Extinction Coeff. Reduced 11920.00

Extinction Coeff. Oxidized 12045.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7884.26

LogP -88.64

H-bond Donors 267.0

H-bond Acceptors 280.0

Rotatable Bonds 649.0

Heavy Atoms 1426.0

Ring Count 34.0

Amide Bonds 200.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0145119 VERIFIED: NO

Provenance & Taxonomy

OrganismCalcarius ornatus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria