Peptide Database

Peptide NameiNGR

Function Ontology

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC35H60N16O13S2

DescriptionStandard

        CRNGRGPDC
    

Molecular Weight977.08 Da

Isoelectric Point (pI)8.07

Net Charge (pH 7.0)0.74

Net Charge (pH 7.4) 0.51

Charge Density (pH 7.0) 0.0824

GRAVY Index-1.49

Hydrophobic Moment 0.42

Boman Index-0.56

Instability Index-11.91

Aliphatic Index 0.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 491.52

LogP -8.22

H-bond Donors 19.0

H-bond Acceptors 16.0

Rotatable Bonds 30.0

Heavy Atoms 66.0

Ring Count 1.0

Amide Bonds 9.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0421612 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyiNGR

Tax ID32630

Structure & Mods

Configcyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Disulfide1-9

Bio-Activity Profile

Function

Cell-penetrating peptide Cargo delivery Tumor-homing Tumor-penetrating CD13-targeting NRP1-dependent penetration

TargetCD13/NRP1-expressing HUVECs; tumor vasculature/tissue

MethodFAM-labeled peptide binding; tumor-homing and penetration assay