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MYP_026427
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Basic Information
Cyclic cationic V1 peptide
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
19 amino acids
C89H167N25O21S2
Standard
Sequence
CVKVKVKVGSGVKVKVKVC
Physicochemical Analysis
1987.56 Da
10.05
5.73
5.49
0.3018
0.72
0.36
0.05
-34.87
122.11
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
763.47
-5.74
29.0
29.0
72.0
137.0
0.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0195184 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Hemolytic
Human erythrocyte
880 μM
EC50
PMID15328096 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15328096/
RECORD: Rec_0226101 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Shigella sonnei ATTC 25931
0.005 μM
MIC
PMID15328096 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15328096/
RECORD: Rec_0265945 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Human erythrocytes
880000
EC50
Paperhttps://pubmed.ncbi.nlm.nih.gov/15328096/ PMID15328096 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15328096/
RECORD: Rec_0361100 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes
50 %
Hemolysis
PaperPubMed PMID: 15328096 PMID15328096 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15328096/
RECORD: Rec_0396967 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Salmonella enterica serovar Typhimurium ATTC 14028
0.005 μM
MIC
PMID15328096 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15328096/
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