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MYP_026422
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Basic Information
ChBac3.4-1-COOH
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
27 amino acids
C172H256N52O29
Standard
Sequence
RFRLPFRRIHPPPFVRIHPPPFYRRFL
Physicochemical Analysis
3516.20 Da
12.00
6.93
6.63
0.2568
-0.58
0.59
-0.20
121.94
68.52
0.2222
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1269.28
-3.68
45.0
38.0
99.0
253.0
15.0
26.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0286339 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human PBMC (50% Cytotoxicity at 12.1+-0.8 microM, Human PBMC (50% Cytotoxicity at 33.7+-3.2 microM
0.8 μM
Hemolysis
PMID33194795 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33194795/
RECORD: Rec_0303976 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human myelogenous leukemia K562
16.5
IC50
PMID33194795 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33194795/
RECORD: Rec_0364475 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa 522/17
16 μM
MIC
PMID33194795 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33194795/
RECORD: Rec_0375925 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus SG511
0.25 μM
MIC
PMID33194795 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33194795/
RECORD: Rec_0381478 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes: <5% Hemolysis=64 μM
PMID33194795 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33194795/
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