Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length356 amino acids

Chemical FormulaC1812H2816N466O494S9

DescriptionStandard

        TNPGFVVRITQSGLDYAQQQGIAVLEKKLASVKLPDISGDSRIKVLGKVYYELSRLDLSGFHLPYSRISLVPNVGLKVSIANAFAKVKGNWRVKLRIIRAHGSFDLTVENTNIDIILRLGNDASGKPTVDTSGCSTRISKVRVRFSGRFGWFYNLFHKVIESKIRKIMEGKVDFLGHVALVHAFVPCFTVTARIDAIAGVDYSLVAPPTASAQSLDVAMKGEFFFMANRSAVPFTPLALTLPPDHDRMVYFAASSYFFNTASFVYHEAGALIFEITDSMITKGTNFHLDTTTFSAFVPQLEGLYPNMRMKFRLFTPSPPFLSIGPEGVSFYPVVDIQAYAILPNSSLVPLFLVSLV
    

Molecular Weight39321.15 Da

Isoelectric Point (pI)9.44

Net Charge (pH 7.0)9.09

Net Charge (pH 7.4) 8.40

Charge Density (pH 7.0) 0.0255

GRAVY Index0.23

Hydrophobic Moment 0.68

Boman Index0.16

Instability Index27.28

Aliphatic Index 98.01

Aromaticity 0.1180

Extinction Coeff. Reduced 28880.00

Extinction Coeff. Oxidized 29005.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0426288 VERIFIED: NO

Provenance & Taxonomy

OrganismPedionomus torquatus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria