Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length321 amino acids

Chemical FormulaC1606H2538N398O446S15

DescriptionStandard

        MDILFHGGASWVLQKFVTQFKQQIQSQVQEKICPTFERGIQGLESHLAAMNVSIPLYRVLLLDMPLTSSPAIQASDLSLDFKGEFYSAQCPKEPPFVSKKFQLPPQERFMLTLGVSEFCLNSAAFAYMSTGLLQINITDKMIPPHFPIHLNTSSFGQFVPQLPKLYPNMLMLFHVYASSTPLVSFLPDNATLLLSASAKAYAIKPNSSALIPLFRLDLSANIGGKFFVEDMMLKGSLMLNNFTLTLGASEVGTFSTLPLQKVLNVGITTMALPLLNAKLKHGLPIPAIKNVNLSNTVLKVNKGFVAVATDAAGSALEEGQL
    

Molecular Weight35038.70 Da

Isoelectric Point (pI)8.66

Net Charge (pH 7.0)3.01

Net Charge (pH 7.4) 2.38

Charge Density (pH 7.0) 0.0094

GRAVY Index0.28

Hydrophobic Moment 0.72

Boman Index0.21

Instability Index37.98

Aliphatic Index 103.02

Aromaticity 0.0903

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 14565.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0081880 VERIFIED: YES

Provenance & Taxonomy

OrganismAnguilla anguilla [Animal]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic

TargetGram-negative bacteria