Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC475H780N118O137S8

DescriptionStandard

        MKLFLVLLILLFEVSEDTARSRKCFSTIAGYCKKKCMLGEIYDKPCTKGKLCCISESKKNTYQQAIQQPEPSSKPDLKLDYVILPTVTLGTIPQ
    

Molecular Weight10592.50 Da

Isoelectric Point (pI)8.93

Net Charge (pH 7.0)4.44

Net Charge (pH 7.4) 4.11

Charge Density (pH 7.0) 0.0473

GRAVY Index-0.09

Hydrophobic Moment 0.52

Boman Index0.02

Instability Index42.80

Aliphatic Index 94.36

Aromaticity 0.0745

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4111.30

LogP -34.67

H-bond Donors 146.0

H-bond Acceptors 150.0

Rotatable Bonds 359.0

Heavy Atoms 738.0

Ring Count 13.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0089866 VERIFIED: NO

Provenance & Taxonomy

OrganismCapra hircus [Animal]

FamilyDefensin

Tax ID9925

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence