Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC303H506N106O88S8

DescriptionStandard

        RCSKACWVLRGHCRKHCRSGERVRKPCSNGDYCCTASKMNHLPQAPKNALSRTGSVPVAVLKSDNK
    

Molecular Weight7298.44 Da

Isoelectric Point (pI)9.93

Net Charge (pH 7.0)10.95

Net Charge (pH 7.4) 10.48

Charge Density (pH 7.0) 0.1659

GRAVY Index-0.74

Hydrophobic Moment 0.79

Boman Index-0.28

Instability Index49.80

Aliphatic Index 53.18

Aromaticity 0.0303

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3166.58

LogP -42.11

H-bond Donors 120.0

H-bond Acceptors 110.0

Rotatable Bonds 243.0

Heavy Atoms 505.0

Ring Count 10.0

Amide Bonds 70.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0067197 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyDefensin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

PaperCross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract PMID16033865 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16033865/; https://www.uniprot.org/uniprotkb/Q30KP4/entry; https://bblserver.org.in/ampdb/

RECORD: Rec_0142814 VERIFIED: NO