Peptide Database

Peptide NameSLAY-screened peptide P1041

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC117H187N37O25

DescriptionStandard

        FNLILLRRLAAWRRKSYTPH
    

Molecular Weight2511.97 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)4.85

Net Charge (pH 7.4) 4.59

Charge Density (pH 7.0) 0.2423

GRAVY Index-0.39

Hydrophobic Moment 0.52

Boman Index-0.19

Instability Index81.80

Aliphatic Index 107.50

Aromaticity 0.1500

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1029.30

LogP -6.30

H-bond Donors 39.0

H-bond Acceptors 31.0

Rotatable Bonds 80.0

Heavy Atoms 179.0

Ring Count 6.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0293531 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/