Peptide Database

Peptide NameTheta defensin subunit B (BTD-b) (BTD-1 subunit 2) (BTD-2)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC347H577N109O106S6

DescriptionStandard

        MRTFALLTAMLLLVALQPQAEARQARADEAAAQQQPGADDQGMAHSFTRPENAALPLSESAKGLRCVCRRGVCQLL
    

Molecular Weight8164.35 Da

Isoelectric Point (pI)7.76

Net Charge (pH 7.0)0.57

Net Charge (pH 7.4) 0.25

Charge Density (pH 7.0) 0.0075

GRAVY Index-0.09

Hydrophobic Moment 0.73

Boman Index-0.02

Instability Index45.43

Aliphatic Index 87.63

Aromaticity 0.0263

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3468.95

LogP -39.44

H-bond Donors 121.0

H-bond Acceptors 114.0

Rotatable Bonds 272.0

Heavy Atoms 568.0

Ring Count 7.0

Amide Bonds 84.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0056758 VERIFIED: YES

Provenance & Taxonomy

OrganismPapio anubis [Animal]

FamilyAlpha-defensin; Defensin

Tax ID9555

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetEscherichia coli (Gram-negative)

RECORD: Rec_0067338 VERIFIED: YES

Provenance & Taxonomy

OrganismPapio anubis [Animal]

FamilyAlpha-defensin; Defensin

Tax ID9555

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetStaphylococcus aureus (Gram-positive)

RECORD: Rec_0384985 VERIFIED: YES

Provenance & Taxonomy

OrganismPapio anubis [Animal]

FamilyAlpha-defensin; Defensin

Tax ID9555

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetCandida albicans