Peptide Database

Peptide NamePhylloseptin-3.3TR

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Immunology ▸ Inflammation modulation ▸ Anti-inflammatory

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC97H159N21O25S

DescriptionStandard

        FFSMIPKIATGIASLVKDL
    

Molecular Weight2051.49 Da

Isoelectric Point (pI)8.59

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.55

Charge Density (pH 7.0) 0.0400

GRAVY Index1.09

Hydrophobic Moment 0.59

Boman Index0.42

Instability Index-6.96

Aliphatic Index 128.42

Aromaticity 0.1053

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 728.36

LogP -3.47

H-bond Donors 25.0

H-bond Acceptors 27.0

Rotatable Bonds 67.0

Heavy Atoms 144.0

Ring Count 3.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0001280 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa trinitatis [Animal]

FamilyPhylloseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetCandida albicans

Activity100 μM

MethodMIC

RECORD: Rec_0001369 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa trinitatis [Animal]

FamilyPhylloseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetS. epidermis

Activity100 μM

MethodMIC

RECORD: Rec_0028590 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa trinitatis [Animal]

FamilyPhylloseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Anticancer Anti-inflammatory Cytotoxic Hemolytic

TargetStaphylococcus epidermidis

RECORD: Rec_0089258 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa trinitatis [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antifungal

TargetCandida albicans

Activity100 μM

MethodMIC

RECORD: Rec_0112875 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa trinitatis [Animal]

FamilyPhylloseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli

Activity100 μM

MethodMIC

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