Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length473 amino acids

Chemical FormulaC2337H3674N580O677S24

DescriptionStandard

        MLHFVIVALMLLPHTCGQNPAIQVLLTNKGLQYGKHVGAEWIQDMLDHVTLPDIQGTFSTLFGPVSYTLSGITITKCDFPEPNVEYSQEYSGFKTSITDLSVALSGNWATKFGILHESGSFDMAIFGVDVTSVVKLEGKADGHLSVSSIICDGEVQDVDIRLYGGFSWIFQPFVHYMKGHIIEEIRKNICPAVQTSIEELESHLQAMNVSFDVNQVLSLELPLSGSPVVSPSNLTLGLKGEFYSIQTHAEPPFKSKPFMMPNIPGYMLSAGVSEFTLNSAAYGYFSAGKLQILITEKMVPKFSPIHLNTSSMGPYIPQLPKLFPGLPMTLQVYATEAPTFSLQSDIVNLTVRAAVKASAVESNGSSIPLFGVNVVVMLSGKMWIADGKVKGSVMLNNFTLTLASTQVGPFKTDSLENMCKKGIELFGVPQVNKKLAEGVMLPRMKRIQPVNSILTVEKGFIAISSDAQVLDML
    

Molecular Weight51497.21 Da

Isoelectric Point (pI)5.78

Net Charge (pH 7.0)-7.55

Net Charge (pH 7.4) -8.50

Charge Density (pH 7.0) -0.0160

GRAVY Index0.20

Hydrophobic Moment 0.60

Boman Index0.20

Instability Index40.77

Aliphatic Index 97.82

Aromaticity 0.0867

Extinction Coeff. Reduced 39880.00

Extinction Coeff. Oxidized 40130.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0353804 VERIFIED: NO

Provenance & Taxonomy

OrganismOryzias sinensis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria

MethodQualitative functional evidence