Peptide Database

Peptide NameANP'

Function Ontology

Natriuretic

Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC116H193N43O37S

DescriptionStandard

        SLRRSSGGRIDRIGAQSGLGCNSFRY
    

Molecular Weight2814.10 Da

Isoelectric Point (pI)11.42

Net Charge (pH 7.0)3.45

Net Charge (pH 7.4) 3.23

Charge Density (pH 7.0) 0.1327

GRAVY Index-0.64

Hydrophobic Moment 0.59

Boman Index-0.25

Instability Index75.94

Aliphatic Index 63.85

Aromaticity 0.0769

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1345.18

LogP -20.11

H-bond Donors 52.0

H-bond Acceptors 42.0

Rotatable Bonds 96.0

Heavy Atoms 197.0

Ring Count 2.0

Amide Bonds 27.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0088592 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyNatriuretic peptide

Structure & Mods

Configcyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Natriuretic

MethodRadioimmunoassay and RP-HPLC

Half-LifeRat blood plasma (infused into fumoral vein and right carotid artery), in vivo; 62.4 s