Peptide Database

Peptide NameCrustacean hyperglycemic hormone

Function Ontology

Developmental biology ▸ Molting regulation

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length72 amino acids

Chemical FormulaC374H587N101O113S7

DescriptionStandard

        AILDQSCKGIFDRELFKKLDRVCDDCYNLYRKPYVAIDCREGCYQNLVFRQCIQDLQLMDQLDEYANAVQIV
    

Molecular Weight8530.73 Da

Isoelectric Point (pI)4.66

Net Charge (pH 7.0)-3.25

Net Charge (pH 7.4) -3.55

Charge Density (pH 7.0) -0.0452

GRAVY Index-0.26

Hydrophobic Moment 0.85

Boman Index-0.08

Instability Index27.38

Aliphatic Index 96.11

Aromaticity 0.1111

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7825.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3534.09

LogP -29.48

H-bond Donors 125.0

H-bond Acceptors 117.0

Rotatable Bonds 289.0

Heavy Atoms 595.0

Ring Count 9.0

Amide Bonds 81.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0126184 VERIFIED: NO

Provenance & Taxonomy

OrganismMacrobrachium lanchesteri [Animal]

FamilyArthropod CHH/MIH/GIH/VIH hormone

Tax ID82204

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide Arthropod neurohormone

RECORD: Rec_0143065 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0378998 VERIFIED: NO

Provenance & Taxonomy

OrganismMacrobrachium lanchesteri [Animal]

FamilyCrustacean hyperglycemic hormone

Tax ID82204

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide7-43; 23-39; 26-52

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Molting regulator

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour