Peptide Database

Peptide NameGlycoprotein hormones alpha chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length96 amino acids

Chemical FormulaC472H735N131O139S15

DescriptionStandard

        FPDGEFTMQDCPECKPRENKFFSKPGAPIYQCMGCCFSRAYPTPVRSKKTMLVQKNVTSESTCCVAKSLTRVMVMGSVRVENHTECHCSTCYYHKF
    

Molecular Weight10949.65 Da

Isoelectric Point (pI)8.72

Net Charge (pH 7.0)4.93

Net Charge (pH 7.4) 4.40

Charge Density (pH 7.0) 0.0514

GRAVY Index-0.42

Hydrophobic Moment 0.64

Boman Index-0.08

Instability Index50.24

Aliphatic Index 39.48

Aromaticity 0.1042

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6585.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4331.53

LogP -47.93

H-bond Donors 160.0

H-bond Acceptors 162.0

Rotatable Bonds 354.0

Heavy Atoms 757.0

Ring Count 20.0

Amide Bonds 101.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0028600 VERIFIED: YES

Provenance & Taxonomy

OrganismMacaca mulatta [Animal]

FamilyGlycoprotein hormones

Tax ID9544

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Disulfide11-35; 14-64; 32-86; 36-88; 63-91

Other Mods56:N-linked (GlcNAc...) asparagine; 82:N-linked (GlcNAc...) asparagine

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator Receptor modulation

Half-LifeMammalian: 1.1 hour; Yeast: 3 min; E. coli: 2 min