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MYP_026208
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Basic Information
Gaegurin-5
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
24 amino acids
C119H203N29O28S2
Standard
Sequence
FLGALFKVASKVLPSVKCAITKKC
Physicochemical Analysis
2552.19 Da
9.90
4.74
4.50
0.1973
0.86
0.57
0.22
7.56
113.75
0.0833
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
914.62
-5.75
34.0
35.0
86.0
178.0
3.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0279745 VERIFIED: YES
Provenance & Taxonomy
Rana rugosa [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes
7 %
Hemolysis
PaperPubMed PMID: 16884301 PMID16884301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16884301/
RECORD: Rec_0289499 VERIFIED: YES
Provenance & Taxonomy
Rana rugosa [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
A549
145.72 μg/mL
IC50
PaperPubMed PMID: 16884301 PMID16884301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16884301/
RECORD: Rec_0293281 VERIFIED: YES
Provenance & Taxonomy
Rana rugosa [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 16884301 PMID16884301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16884301/
RECORD: Rec_0344970 VERIFIED: YES
Provenance & Taxonomy
Rana rugosa [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
MCF-7
183.74 μg/mL
IC50
PaperPubMed PMID: 16884301 PMID16884301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16884301/
RECORD: Rec_0404941 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
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