Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length97 amino acids

Chemical FormulaC485H772N134O144S10

DescriptionStandard

        AAMKIIHIISIFVFSVSCGPSVPQKKTREAAERKRECYLVRGACKSECNTWEYIFNYCDTEPCCVVREYQKPITRAMLSTTHTNVNYTADTLKNSML
    

Molecular Weight11104.78 Da

Isoelectric Point (pI)8.73

Net Charge (pH 7.0)3.91

Net Charge (pH 7.4) 3.49

Charge Density (pH 7.0) 0.0403

GRAVY Index-0.24

Hydrophobic Moment 0.78

Boman Index-0.04

Instability Index34.48

Aliphatic Index 72.37

Aromaticity 0.0928

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13325.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4510.61

LogP -45.87

H-bond Donors 166.0

H-bond Acceptors 160.0

Rotatable Bonds 365.0

Heavy Atoms 773.0

Ring Count 16.0

Amide Bonds 103.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0299275 VERIFIED: NO

Provenance & Taxonomy

OrganismFukomys damarensis [Animal]

FamilyBeta-defensin; Defensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic