Peptide Database

Peptide NameNeuropeptide S precursor

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Sleep regulation

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC330H542N94O90S2

DescriptionStandard

        YPVLSSKVPGKPDYFLILLSSCPARLEGSDRLAFLKPILEKTSMKRSFRNGVGSGAKKTSFRRAKQ
    

Molecular Weight7330.54 Da

Isoelectric Point (pI)10.55

Net Charge (pH 7.0)9.75

Net Charge (pH 7.4) 9.51

Charge Density (pH 7.0) 0.1477

GRAVY Index-0.39

Hydrophobic Moment 0.65

Boman Index-0.12

Instability Index52.45

Aliphatic Index 78.33

Aromaticity 0.0909

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2988.80

LogP -30.22

H-bond Donors 108.0

H-bond Acceptors 102.0

Rotatable Bonds 247.0

Heavy Atoms 516.0

Ring Count 11.0

Amide Bonds 67.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0181098 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyNeuropeptide S precursor

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide Neuromodulator Receptor modulation Immunomodulatory ACE inhibitory Sleep regulation Wake regulation

Half-LifeMammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min