MYP_026184
Melittin
Anticancer
Anticancer
▸
Cytotoxic anticancer activity
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Cytotoxic
Antimicrobial
Antimicrobial
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Antibacterial
Antimicrobial
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Antibacterial
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Anti-Gram-negative
Antimicrobial
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Antibacterial
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Anti-Gram-positive
Antimicrobial
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Antibacterial
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Anti-Mycobacterium
Antimicrobial
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Anti-biofilm
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Biofilm inhibition
Antimicrobial
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Antifungal
Antiparasitic
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Anti-Leishmania
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Antileishmanial
Antiparasitic
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Antiprotozoal
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Anti-Trypanosoma
Antiparasitic
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General antiparasitic
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Antiparasitic
Antiviral
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Anti-Herpesvirus
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Antiviral
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Antiviral
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Anti-HIV
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Antiviral
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Anti-Pneumovirus
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Antiviral
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Antiviral mechanism
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Viral entry inhibition
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Antiviral
▸
Antiviral mechanism
▸
Delivery / Targeting
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Cell penetration
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Cell-penetrating peptide
Delivery / Targeting
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Drug delivery vehicle
Enzyme modulation
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Enzyme inhibition
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Gene expression inhibitor
Insecticidal/Pest control
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Insecticidal activity
Neurological / Signaling
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Neuropeptide activity
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Neuropeptide
Toxicity / Safety
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Blood cell toxicity
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Hemolysis
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Hemolytic
Toxicity / Safety
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Cytolysis / cell lysis
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Cytolytic activity
Toxicity / Safety
▸
Cytotoxicity
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Cytotoxic
Venom / Toxin
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General toxin
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Cytotoxic
Venom / Toxin
▸
General toxin
▸
Toxic
Venom / Toxin
▸
General toxin
▸
Toxin
Venom / Toxin
▸
Toxin
Standard
26 amino acids
C131H228N38O32
Standard
GIGAVLKVLTTGLPALISWIKRKRQQ
2847.45 Da
12.00
4.76
4.55
0.1830
0.27
0.57
0.10
44.73
135.00
0.0385
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1146.55
-8.48
41.0
37.0
97.0
201.0
3.0
27.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0128455
VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
FLAK peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer
Cytotoxic
PC-3
13 μg/mL
LD50
RECORD: Rec_0130853
VERIFIED: YES
Provenance & Taxonomy
Apis mellifera [Animal]
7460
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anti-RSV
Fusion inhibition
GFP-fused RSV | HEp-2 cellss
0.3477±0.03161 μM
EC50
Mammalian: 30 h; Yeast: >20 h; E. coli: >10 h
RECORD: Rec_0130947
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin-derived peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer
BMKC
18.0 μg/mL
LD50 / MTT-MTS assay
RECORD: Rec_0131127
VERIFIED: YES
Provenance & Taxonomy
Apis mellifera [Animal]
Melittin
7460
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial
Antifungal
Anticancer
Antiparasitic
Insecticidal
Escherichia coli W 160-37
5-10 μg/mL
MIC
RECORD: Rec_0131934
VERIFIED: YES
Provenance & Taxonomy
Apis mellifera [Animal]
Melittin
7460
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-negative
HIV
Showing 5 records on this page · Page 6 of 23