Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length477 amino acids

Chemical FormulaC2378H3694N632O671S13

DescriptionStandard

        MKLSLSLALGLLFALLALASAAHPGFKVTLTESGLNYAREVAVEYLEKRFATVHVPDESGDAHAPVVGKIKWELKDIVMSGLRLPRSSINILPGRGVAVSIDQAALEIKMNFHYREHHWPHIKGHGHLVIHASGINIAVDIHVGEQNARPTMSVISSHCSIGDLSIKEHGGPSWLYNFFLKVLHKMIQKAAEKAVGSSIENLLNHGGNEALQTIPLAERFSNIAEVDYSLVGGPTFGHNYLTINAKGEFYYLPHKQEAPFAAQPMPDEINGEMMQIMLSDFVPDSASFVFRESGKMTHILQDKDLPKWAPIRLNTNSWSHILPDLTKKYPNLEMQAELHTTSPPKATFSHDGIRVAGPGQVVVSVLPHGGAPVPVFALNIDLTTSAKVTVRDGRIFTELSYLQSPITVAFSHVGTITVSEVDHIIKTLCTDAIVPFFNYYLSHGVNIPTIKGVHFVEPHIAYGPSYLAIATNIHYTG
    

Molecular Weight52289.44 Da

Isoelectric Point (pI)6.54

Net Charge (pH 7.0)-4.03

Net Charge (pH 7.4) -5.80

Charge Density (pH 7.0) -0.0084

GRAVY Index0.03

Hydrophobic Moment 0.73

Boman Index0.16

Instability Index44.26

Aliphatic Index 97.92

Aromaticity 0.0839

Extinction Coeff. Reduced 49850.00

Extinction Coeff. Oxidized 49975.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0263501 VERIFIED: NO

Provenance & Taxonomy

OrganismAcanthamoeba castellanii str. Neff [Protist]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence