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MYP_026144
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Basic Information
KT2
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
17 amino acids
C126H164N30O21
Standard
Sequence
NGVQPKYKWWKWWKKWW
Physicochemical Analysis
2434.84 Da
10.30
4.75
4.54
0.2797
-1.82
0.63
-0.14
11.90
17.06
0.4118
34490.00
34490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
851.38
2.03
31.0
26.0
72.0
177.0
14.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0116020 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis
PMID27129462 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27129462/
RECORD: Rec_0122286 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 25923
46
MIC
PMID23831136 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23831136/
RECORD: Rec_0149204 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0169254 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
11
MIC
PMID23831136 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23831136/
RECORD: Rec_0184859 VERIFIED: YES
Provenance & Taxonomy
AMP [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
HCT 116
50 μM
IC50
PaperPubMed PMID: 31073999 PMID31073999 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31073999/
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