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MYP_026144
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Basic Information
KT2
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
17 amino acids
C126H164N30O21
Standard
Sequence
NGVQPKYKWWKWWKKWW
Physicochemical Analysis
2434.84 Da
10.30
4.75
4.54
0.2797
-1.82
0.63
-0.14
11.90
17.06
0.4118
34490.00
34490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
851.38
2.03
31.0
26.0
72.0
177.0
14.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0011274 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
5
MIC
PMID25767037 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25767037/
RECORD: Rec_0036580 VERIFIED: YES
Provenance & Taxonomy
AMP [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
MDA-MB-231 (Not active up to 10 μM)
PaperPubMed PMID: 31073999 PMID31073999 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31073999/
RECORD: Rec_0037165 VERIFIED: YES
Provenance & Taxonomy
AMP [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
A431
34 %
Cytotoxicity
PaperPubMed PMID: 31073999 PMID31073999 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31073999/
RECORD: Rec_0068287 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
B. pumilus TISTR 905
PMID27129462 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27129462/
RECORD: Rec_0075922 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
V. cholerae
PMID27129462 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27129462/
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