Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length105 amino acids

Chemical FormulaC528H821N143O137S4

DescriptionStandard

        MVLLAVTEFVANSAAFAYFTAGALRRNISSGTLPRRFPLQLTTKSVGGFCPQLQQRYPDLPMELQLWARQPPLLSCHPHGLHGVLFASAEAFVVLPNASRVPAFL
    

Molecular Weight11492.30 Da

Isoelectric Point (pI)9.83

Net Charge (pH 7.0)3.75

Net Charge (pH 7.4) 3.34

Charge Density (pH 7.0) 0.0357

GRAVY Index0.30

Hydrophobic Moment 0.45

Boman Index0.18

Instability Index65.87

Aliphatic Index 97.62

Aromaticity 0.1048

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4383.20

LogP -37.11

H-bond Donors 151.0

H-bond Acceptors 148.0

Rotatable Bonds 356.0

Heavy Atoms 812.0

Ring Count 25.0

Amide Bonds 113.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0088383 VERIFIED: NO

Provenance & Taxonomy

OrganismMesitornis unicolor [Animal]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic

TargetGram-negative bacteria