Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length184 amino acids

Chemical FormulaC928H1408N210O288S10

DescriptionStandard

        QIDDLAEVDYSLSSFPAVFRPFIDLDLKGMVFPAGNYTDSPYVPASFTIPDQSDSMLYLAFSEYFFQTSSFAYYTTGAFNMTIAEETCSYFNINTEIFGTIIPEVAKYSVTPNPVMLKLMATEVPIISLEQDSFTVEIQGSMEVLAVLPDSTTQSLFTMNIAANTSISLNIFDQKLMGSLCLNR
    

Molecular Weight20434.99 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-15.23

Net Charge (pH 7.4) -15.51

Charge Density (pH 7.0) -0.0828

GRAVY Index0.23

Hydrophobic Moment 0.61

Boman Index0.22

Instability Index46.04

Aliphatic Index 87.99

Aromaticity 0.1304

Extinction Coeff. Reduced 13410.00

Extinction Coeff. Oxidized 13535.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7902.90

LogP -87.41

H-bond Donors 268.0

H-bond Acceptors 283.0

Rotatable Bonds 652.0

Heavy Atoms 1436.0

Ring Count 35.0

Amide Bonds 199.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0124773 VERIFIED: NO

Provenance & Taxonomy

OrganismFalcunculus frontatus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria