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MYP_026031
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Basic Information
Unnamed
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
21 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
IELLQARGGCXGGRRRRRRRR
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0149351 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
mixed L/D or residue-modified peptide [Mixed]
None
Amidation
Pem= Pemetrexed
Bio-Activity Profile
Anticancer
PaperCancerPPD: a database of anticancer peptides and proteins PMID25270878 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25270878/
RECORD: Rec_0188597 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Pem= Pemetrexed
Bio-Activity Profile
Anticancer Cytotoxic
HL-60
2.64 μM
IC50
PMID22076954 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22076954/
RECORD: Rec_0194652 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
X(11)=Pemetrexed
Bio-Activity Profile
Antimicrobial Anticancer
HL-60
2.64 μM
IC50
PaperPubMed PMID: 22076954 PMID22076954 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22076954/
RECORD: Rec_0200145 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
X(11)=Pemetrexed
Bio-Activity Profile
Antimicrobial Anticancer
NCI-H358
2.19 μM
IC50
PaperPubMed PMID: 22076954 PMID22076954 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22076954/
RECORD: Rec_0209085 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
X(11)=Pemetrexed
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 22076954 PMID22076954 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22076954/
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