Peptide Database

Peptide NameTransforming growth factor alpha

Function Ontology

Mitogenic

Standard StatusStandard

Sequence Length50 amino acids

Chemical FormulaC238H352N70O72S6

DescriptionStandard

        VVSHFNDCPDSHSQFCFHGTCRFLVQEDKPACVCHSGYVGARCEHADLLA
    

Molecular Weight5538.16 Da

Isoelectric Point (pI)5.85

Net Charge (pH 7.0)-2.88

Net Charge (pH 7.4) -3.44

Charge Density (pH 7.0) -0.0576

GRAVY Index-0.08

Hydrophobic Moment 0.46

Boman Index0.05

Instability Index26.34

Aliphatic Index 60.40

Aromaticity 0.1000

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2239.31

LogP -25.07

H-bond Donors 82.0

H-bond Acceptors 80.0

Rotatable Bonds 173.0

Heavy Atoms 386.0

Ring Count 12.0

Amide Bonds 52.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0254218 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

Tax ID9823

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide8-21; 16-32; 34-43

Bio-Activity Profile

Function

Mitogenic