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MYP_026022
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Basic Information
Bombinin-BO1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
22 amino acids
C91H165N25O26
Standard
Sequence
GIGSAILSAGKSIIKGLAKGLA
Physicochemical Analysis
2025.44 Da
10.30
2.76
2.55
0.1253
0.93
0.67
0.39
-1.00
142.27
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
813.17
-8.50
29.0
29.0
72.0
142.0
0.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0033568 VERIFIED: YES
Provenance & Taxonomy
skin secretion of Oriental fire-bellied toad,Bombina orientalis [Animal]
Bombinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Huh-7
3.91 μM
IC50
PaperPubMed PMID: 29098406 PMID29098406 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29098406/
RECORD: Rec_0106147 VERIFIED: YES
Provenance & Taxonomy
skin secretion of Oriental fire-bellied toad,Bombina orientalis [Animal]
Bombinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
SK-HEP-1
3.75 μM
IC50
PaperPubMed PMID: 29098406 PMID29098406 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29098406/
RECORD: Rec_0111496 VERIFIED: YES
Provenance & Taxonomy
skin secretion of Oriental fire-bellied toad,Bombina orientalis [Animal]
Bombinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human Red cells: only 2
PaperPubMed PMID: 29098406 PMID29098406 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29098406/
RECORD: Rec_0115448 VERIFIED: YES
Provenance & Taxonomy
skin secretion of Oriental fire-bellied toad,Bombina orientalis [Animal]
Bombinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Hep-G2
0.76 μM
IC50
PaperPubMed PMID: 29098406 PMID29098406 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29098406/
RECORD: Rec_0208476 VERIFIED: YES
Provenance & Taxonomy
skin secretion of Oriental fire-bellied toad,Bombina orientalis [Animal]
Bombinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 29098406 PMID29098406 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29098406/
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