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MYP_025972
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Basic Information
Hepcidin (fish, chordates, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Standard
21 amino acids
C98H165N39O22S9
Standard
Sequence
RCRFCCRCCPRMRGCGICCRF
Physicochemical Analysis
2530.19 Da
9.22
5.68
5.36
0.2705
0.12
0.65
-0.35
3.43
18.57
0.0952
0.00
500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1007.93
-11.83
47.0
37.0
81.0
168.0
3.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0206019 VERIFIED: YES
Provenance & Taxonomy
Larimichthys crocea [Animal]
Hepcidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Aeromonas hydrophila
Evidence URLhttps://www.uniprot.org/uniprotkb/A1Z0M0/entry
RECORD: Rec_0206196 VERIFIED: YES
Provenance & Taxonomy
Larimichthys crocea [Animal]
Hepcidin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
2-19, 5-8, 6-15, 9-18
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli
24 μM
MIC
PMID19150638;19344770 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19150638/
RECORD: Rec_0242098 VERIFIED: YES
Provenance & Taxonomy
Larimichthys crocea [Animal]
Hepcidin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
2-19, 5-8, 6-15, 9-18
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Aeromonas hydrophila
6 μM
MIC
PMID19150638;19344770 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19150638/
RECORD: Rec_0242275 VERIFIED: YES
Provenance & Taxonomy
Larimichthys crocea [Animal]
Hepcidin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
2-19, 5-8, 6-15, 9-18
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Vibrio alginolyticus
24 μM
MIC
PMID19150638;19344770 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19150638/
RECORD: Rec_0253086 VERIFIED: YES
Provenance & Taxonomy
Larimichthys crocea [Animal]
Hepcidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Micrococcus lysodeikticus Staphylococcus aureus
Evidence URLhttps://www.uniprot.org/uniprotkb/A1Z0M0/entry
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