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MYP_025964
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Basic Information
WR8
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
9 amino acids
C59H108N34O10
Standard
Sequence
WRRRRRRRR
Physicochemical Analysis
1453.71 Da
12.00
7.76
7.56
0.8622
-4.10
0.25
-2.16
454.40
0.00
0.1111
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
807.11
-8.89
35.0
18.0
51.0
103.0
2.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0279033 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Source entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata
Conjugate type: amide; Conjugated small molecule: Deacetylvinblastine
Bio-Activity Profile
Anticancer
PaperSynthesis and in Vitro Antitumor Effect of Vinblastine Derivative-Oligoarginine Conjugates Evidence URLhttps://doi.org/10.1021/bc100028z
RECORD: Rec_0293440 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 33591
44 μM
MIC
PMID22989747 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22989747/
RECORD: Rec_0336423 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Proteus mirabilis
64 μg/mL
MIC
PMID22989747 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22989747/
RECORD: Rec_0360942 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa
64 μg/mL
MIC
PMID22989747 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22989747/
RECORD: Rec_0380471 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus
32 μg/mL
MIC
PMID22989747 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22989747/
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